Myelin injury precedes axonal injury and symptomatic onset in multiple sclerosis.

Abdelhak A, Cerono G, Sheikhzadeh F, Harroud A, Ning K, Zamecnik CR, Sowa GM, Boscardin J, Cordano C, Tubati A, Fouassier C, Chow ED, Gomez R, Santaniello A, Zorn KC, Hollenbach JA, Oksenberg JR, Cree BAC, Hauser SL, Chan JR, Baranzini SE, Wallin MT, Wilson MR, Green AJ. Myelin injury precedes axonal injury and symptomatic onset in multiple sclerosis. Nat Med. 2026 Jan; 32(1):362-368.