Publications

Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study.

Yoon H, Gerdes LA, Beigel F, Sun Y, Kövilein J, Wang J, Kuhlmann T, Flierl-Hecht A, Haller D, Hohlfeld R, Baranzini SE, Wekerle H, Peters A

Proceedings of the National Academy of Sciences of the United States of America, 2025

A disease-specific convergence of host and Epstein-Barr virus genetics in multiple sclerosis.

Mechelli R, Umeton R, Bellucci G, Bigi R, Rinaldi V, Angelini DF, Guerrera G, Pignalosa FC, Ilari S, Patrone M, Srinivasan S, Cerono G, Romano S, Buscarinu MC, Martire S, Malucchi S, Landi D, Lorefice L, Pizzolato Umeton R, Anastasiadou E, Trivedi P, Fornasiero A, Ferraldeschi M, IMSGC WTCCC2, Di Sapio A, Marfia G, Cocco E, Centonze D, Uccelli A, Di Silvestre D, Mauri P, de Candia P, D'Alfonso S, Battistini L, Farina C, Magliozzi R, Reynolds R, Baranzini SE, Matarese G, Salvetti M, Ristori G

Proceedings of the National Academy of Sciences of the United States of America, 2025

A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.

Le T, Htun S, Pandey MK, Sun Y, Magnusen AF, Ullah E, Lauzon J, Beres S, Lee C, Guan B, Hufnagel RB, Brooks BP, Baranzini SE, Slavotinek A

Frontiers in cell and developmental biology, 2025

Multi-disciplinary research will be the key to stop, restore, and end MS.

Baranzini SE

Multiple sclerosis (Houndmills, Basingstoke, England), 2025

Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data.

Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore GD, Sonehara K, Zakeri M, Chen Y, Dilmore AH, Damle N, Baranzini SE, Hightower G, Nakatsuji T, Gallo RL, Langmead B, Okada Y, Curtius K, Knight R

Nature communications, 2025

Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation.

Jank L, Singh SS, Lee J, Dhukhwa A, Siavoshi F, Joshi D, Minney V, Gupta K, Ghimire S, Deme P, Schoeps VA, Soman K, Ladakis D, Smith M, Borkowski K, Newman J, Baranzini SE, Waubant EL, Fitzgerald KC, Mangalam A, Haughey N, Kornberg M, Chamling X, Calabresi PA, Bhargava P

bioRxiv : the preprint server for biology, 2024

Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data.

Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore GD, Sonehara K, Zakeri M, Chen Y, Dilmore AH, Damle N, Baranzini SE, Nakatsuji T, Gallo RL, Langmead B, Okada Y, Curtius K, Knight R

Research square, 2024

Artificial intelligence in food and nutrition evidence: The challenges and opportunities.

Bailey RL, MacFarlane AJ, Field MS, Tagkopoulos I, Baranzini SE, Edwards KM, Rose CJ, Schork NJ, Singhal A, Wallace BC, Fisher KP, Markakis K, Stover PJ

PNAS nexus, 2024

Biomedical knowledge graph-optimized prompt generation for large language models.

Soman K, Rose PW, Morris JH, Akbas RE, Smith B, Peetoom B, Villouta-Reyes C, Cerono G, Shi Y, Rizk-Jackson A, Israni S, Nelson CA, Huang S, Baranzini SE

Bioinformatics (Oxford, England), 2024

Genetics of multiple sclerosis severity: The importance of statistical power in replication studies.

Harroud A, Sawcer SJ, Baranzini SE

Multiple sclerosis (Houndmills, Basingstoke, England), 2024

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