Proceedings of the National Academy of Sciences of the United States of America

Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study.

Proceedings of the National Academy of Sciences of the United States of America

Yoon H, Gerdes LA, Beigel F, Sun Y, Kövilein J, Wang J, Kuhlmann T, Flierl-Hecht A, Haller D, Hohlfeld R, Baranzini SE, Wekerle H, Peters A

A disease-specific convergence of host and Epstein-Barr virus genetics in multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Mechelli R, Umeton R, Bellucci G, Bigi R, Rinaldi V, Angelini DF, Guerrera G, Pignalosa FC, Ilari S, Patrone M, Srinivasan S, Cerono G, Romano S, Buscarinu MC, Martire S, Malucchi S, Landi D, Lorefice L, Pizzolato Umeton R, Anastasiadou E, Trivedi P, Fornasiero A, Ferraldeschi M, IMSGC WTCCC2, Di Sapio A, Marfia G, Cocco E, Centonze D, Uccelli A, Di Silvestre D, Mauri P, de Candia P, D'Alfonso S, Battistini L, Farina C, Magliozzi R, Reynolds R, Baranzini SE, Matarese G, Salvetti M, Ristori G

A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models.

Proceedings of the National Academy of Sciences of the United States of America

Cekanaviciute E, Yoo BB, Runia TF, Debelius JW, Singh S, Nelson CA, Kanner R, Bencosme Y, Lee YK, Hauser SL, Crabtree-Hartman E, Sand IK, Gacias M, Zhu Y, Casaccia P, Cree BAC, Knight R, Mazmanian SK, Baranzini SE

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice.

Proceedings of the National Academy of Sciences of the United States of America

Berer K, Gerdes LA, Cekanaviciute E, Jia X, Xiao L, Xia Z, Liu C, Klotz L, Stauffer U, Baranzini SE, Kümpfel T, Hohlfeld R, Krishnamoorthy G, Wekerle H

Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event.

Proceedings of the National Academy of Sciences of the United States of America

Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg JR, Baranzini SE