The Baranzini Lab is interested in the genetics and molecular mechanisms underlying complex diseases.

In particular, we use a combination of wet and dry lab approaches to investigate the disease multiple sclerosis, an autoimmune disorder of the central nervous system. Work in our lab involves human genetics, immunology, molecular biology, bioinformatics and systems biology approaches.

We are also the creators of SPOKE, an open knowledge network that aims at integrating all publicly available biomedical information into a giant graph. Among other uses, SPOKE is being developed to aid in drug repurposing, precision medicine approaches, and molecular pharmacology.